Research Articles
Full-Length vs 3'-End scRNA-Seq: A Comprehensive Guide to Choosing the Right Protocol for Your Research
This article provides a comprehensive comparison of full-length and 3'-end single-cell RNA sequencing protocols.
Flye vs Canu vs SPAdes: A Comprehensive 2024 Performance Guide for Genomic Researchers
This article provides a detailed, comparative analysis of three leading long-read (Flye and Canu) and short-read (SPAdes) genome assemblers, tailored for researchers and professionals in genomics and drug development.
Complete Guide to Flye Assembly for Oxford Nanopore Sequencing: Protocol, Optimization, and Validation
This comprehensive guide provides researchers, scientists, and drug development professionals with a complete workflow for performing genome assembly using Flye with Oxford Nanopore long-read data.
Mastering Long-Read Assembly: A Comprehensive Guide to Flye for Biomedical Researchers
This guide provides a detailed exploration of the Flye assembler, a leading tool for de novo genome assembly from long-read sequencing data.
Navigating FDA Guidelines for LC-MS/MS Biomarker Assays: A Comprehensive Guide for Drug Development
This definitive guide provides researchers, scientists, and drug development professionals with a detailed roadmap for developing and validating mass spectrometry-based biomarker assays aligned with current FDA expectations.
Applying FAIR Data Principles to Genomic Annotation: A Guide for Biomedical Research and Drug Discovery
This article provides a comprehensive guide for researchers and drug development professionals on implementing FAIR (Findable, Accessible, Interoperable, Reusable) data principles in genomic annotation workflows.
From Phenotype to Transcriptome: A Comprehensive Guide to FACS Sorting for Single-Cell RNA Sequencing
This guide provides a detailed roadmap for researchers, scientists, and drug development professionals leveraging Fluorescence-Activated Cell Sorting (FACS) to isolate single cells for downstream single-cell RNA sequencing (scRNA-seq).
Mastering Exomiser: The Complete Guide to Parameter Optimization for Rare Disease Variant Prioritization
This comprehensive guide addresses the critical challenge of prioritizing causative variants from next-generation sequencing data in rare disease research.
Affinity vs. MS Platforms: A Comprehensive Sensitivity Comparison for Biomarker & Drug Development
This article provides a critical evaluation of the sensitivity of affinity-based (e.g., immunoassays) and mass spectrometry (MS)-based platforms for quantifying proteins and biomarkers.
Ensembl VEP Tutorial 2024: A Beginner's Guide to Variant Annotation for Genomic Research
This comprehensive beginner's guide to the Ensembl Variant Effect Predictor (VEP) walks researchers through the foundational concepts, practical application, troubleshooting, and validation of variant annotations.